IMMUNE

When will my order be shipped out?

All orders ship out the following business day.

What is the difference between PreSeries BULK, PreSeries LEAN, and PreSeries STIM-FREE?

PreSeries BULK is designed to support lean muscle growth and includes a testosterone support complex, while PreSeries LEAN is designed to support fat loss and includes a thyroid support complex. PreSeries STIM-FREE, as the name suggests, contains zero stimulants and has added elevATP.

Does Transparent Labs ship to my Country?

EpiCor® remains one of the most promising immune-promoting ingredients on the market. By using an innovative anaerobic fermentation process, EpiCor® provides a bioactive-rich fermentate from dried baker’s yeast (Saccharomyces cerevisiae). 

In contrast to pure beta-glucans and yeast cell wall preparations, EpiCor® yeast fermentate contains an array of bioactive metabolites, vitamins, phospholipids, cell wall constituents, and stress-induced defense mediators. After ingestion, EpiCor® is rapidly assimilated and activates immune-modulators like natural killer cells while also boosting antioxidant capacity [1].

A growing body of clinical research suggests that EpiCor® yeast fermentate can help support innate and adaptive immune responses, thereby conferring protection against health challenges when the body is stressed [2, 3].

Ganoderma lucidum, also known as the reishi mushroom, is a large, robust mushroom that has been used as an immune- and liver-revitalizing agent for centuries in Traditional Chinese Medicine [4]. Research suggests that reishi mushrooms contain protein and triterpene constituents, specifically ganodermic acids, with potent immunostimulating and hepatoprotective properties [5]. 

Clinical evidence has shown that ganodermic acids inhibit the release of histamine in mast cells (meaning ganodermic acids work to reduce pro-inflammatory markers in susceptible body tissues) [6]. The distinct proteins in reishi mushrooms also appear to preserve liver function through antioxidant mechanisms [7].

Curcuma longa (turmeric) is a flowering plant whose roots and rhizomes are among the richest natural sources of promising phytochemicals called curcuminoids. The vibrant golden color of turmeric spice derives from these curcuminoids, notably curcumin. Clinical evidence suggests that curcuminoids have ubiquitous roles throughout the body, particularly within the immune system, nervous system, and musculoskeletal system [8]. 

Vis-à-vis immune function, a recent double-blind, placebo-controlled trial found that subjects taking a curcumin supplement had significantly greater reductions in serum concentrations of proinflammatory cytokines compared to those taking a placebo [9]. These results are congruent with a current meta-analysis of clinical studies substantiating the anti-inflammatory properties of curcumin [10].

The catch is that curcuminoids — especially curcumin — have poor oral bioavailability, ostensibly limiting the therapeutic potential of many turmeric supplements on the market [11]. However, recent advancements in biotechnology have made it possible to circumvent the oral absorption issues with curcuminoids, resulting in exceptional bioavailability. 

CurcuWIN® Ultra+ provides highly bioavailable curcuminoids through OmniActive’s proprietary Ultrasol technology, allowing significantly up to 144x more curcumin to reach systemic circulation than standard curcumin formulations [12]. In turn, this translates to more robust immune support and inflammation protection. 

Ginger (Zingiber officinalis) is a flowering plant that has also been used as an herbal anti-nausea and indigestion remedy throughout history. The roots of the plant are a rich source of fragrant polyphenols — known as gingerols — that give ginger its characteristic spice and aroma [13]. 

It is now well-established that several gingerols, notably the congener 6-gingerol, have significant antioxidant and immunomodulatory properties throughout the body [14, 15]. As one of the most potent ginger root extracts available, Gingever® provides a hefty 10% gingerols by mass, ensuring an efficacious dose of these key constituents in every serving of Transparent Labs Immune. 

Magnesium is an essential cofactor (think: “assisting molecule”) for an estimated 300+ biochemical reactions throughout the body [22]. For example, magnesium is a major constituent of bone minerals and a mediator of immune function, skeletal muscle contraction, and nerve impulse transmission. 

Recent studies suggest that the average person does not meet the recommended daily intake for magnesium and may be at risk of (sub)clinical hypomagnesemia [23, 24]. Therefore, bioavailable magnesium supplementation is becoming an important staple for overall health and wellness.

As a crucial water-soluble antioxidant, vitamin C plays many important roles throughout the immune, nervous, and cardiovascular systems. Studies continue to demonstrate that supplementing with vitamin C can reduce the severity and duration of cold and flu symptoms and may hold promise as an adjuvant to existing treatments [27, 28]. 

Biologically active vitamin D performs a multitude of roles in the body and is particularly important for proper absorption of the minerals calcium, iron, magnesium, phosphate, and zinc [29]. Calcitriol also regulates bone growth and regeneration, as well as immune, cardiac, and neuromuscular functions [30].

L-theanine is an amino acid used by the body. When combined with caffeine, L-theanine demonstrates many benefits for athletes, like:

• Increases reaction time, attention, and memory [14, 15, 16, 17]
• Reduces jitters in caffeine sensitive individuals
• Reduces stress and causes relaxation without affecting attention and energy [18].

PreSeries BULK contains 360 mg of L-Theanine per serving.