KSM-66 Ashwagandha
KSM-66 Ashwagandha
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KSM-66 Ashwagandha

High-potency, organic KSM-66® Ashwagandha capsules clinically shown to reduce stress, boost cognitive function, improve mood, and support hormonal balance.

No Artificial Sweeteners

No Artificial Sweeteners

Gluten-Free and Non-GMO

Gluten-Free and Non-GMO

No Artificial Coloring

No Artificial Coloring

No Artificial Preservatives

No Artificial Preservatives

Serving Size:

  • 60 Servings

Third-Party Testing

We believe trust is earned through transparency. That’s why we provide full access to our third-party test results, so you can feel confident in what you’re taking. View all third-party tests.

View product purity test results (Certificate of Analysis)

Transparent Labs KSM-66® capsules are the perfect option if you're after a high-quality, organic, and standardized Ashwagandha (Withania somnifera) extract.


Each capsule provides the clinically studied dose of 600 mg KSM-66®, which is the most extensively studied ashwagandha extract available, standardized to contain 5% bioactive withanolides.


Ashwagandha is arguably the most versatile adaptogenic herb known to man. Its multifunctional benefits are the subject of ongoing research, with studies thus far showing that it controls stress and anxiety, eases inflammation and fights oxidative stress, improves mood and mental performance, promotes healthy metabolic, endocrine, and immune function, and supports sexual function.

Orders in the US over $99 ship free.

Once your order has shipped out from our fulfillment center, you will receive a Shipping Confirmation email. If you selected a tracked shipping method, you will receive your tracking information, along with the necessary steps to track your order, within this email. Please note, orders are generally fulfilled same day or next business day.

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45 Day Satisfaction Guarantee

If you are not satisfied with your product, we will offer you a full refund or store credit for the value of the item within 45 days of delivery.

Click here for the full refund policy »

why use KSM-66 Ashwagandha?

Transparent Labs KSM-66® Ashwagandha is a root extract standardized for 5% withanolides to support stress relief, cognition, hormonal health, and vitality.

Reduces Stress & Anxiety

Lowers cortisol to support stress management, promoting relaxation, emotional stability, and mental clarity.

Reduces Stress & Anxiety

Enhances Cognitive Function

Clinically shown to improve cognitive performance, focus, and overall mental well-being.

Enhances Cognitive Function

Supports Healthy Hormones

Naturally balances cortisol and testosterone, promoting vitality, mood, and sexual function.

Supports Healthy Hormones

Organic & Clinically Validated

Contains standardized, organic ashwagandha root extract with third-party tested purity and potency.

Organic & Clinically Validated

Key Ingredients

Our formulas are made with clean, natural ingredients, with clinically-validated dosages to support health and performance.

KSM-66® Ashwagandha (Withania somnifera Root Extract)

600 mg

A clinically validated, organic adaptogen that reduces cortisol, supports cognition, mood, hormonal balance, muscle recovery, and resilience to physical and mental stress.

KSM-66® Ashwagandha (Withania somnifera Root Extract)

KSM-66® Ashwagandha (Withania somnifera Root Extract)

600 mg

Each batch of KSM-66® ashwagandha extract is standardized to contain 5% withanolides, the primary bioactive constituents in the herb [1]. This specific ashwagandha root extract (KSM-66®) has been clinically evaluated in 24 human studies, a feat that no other ashwagandha extracts have matched [2]. The findings of these studies demonstrate the compelling benefits of KSM-66® for human health and longevity, especially concerning anxiety, chronic stress, sex hormone production, body weight management, and cognitive functions/mental clarity. 

Ashwagandha (Withania somnifera), also known as Indian ginseng, is arguably the most versatile adaptogenic herb known to man. Adaptogenic herbs are so-named because they help the body adapt to and overcome physical and mental stress through diverse mechanisms, such as modulating stress hormone production (e.g., lowering cortisol levels) and attenuating inflammation.

Several recent research reviews comprising preclinical and clinical trials suggest that the health benefits of ashwagandha extract include [3,4]:

  • Controlling stress hormones (e.g., cortisol) and fighting anxiety 
  • Easing inflammation and oxidative stress
  • Enhancing mood and mental performance
  • Promoting healthy metabolic, endocrine, and immune function
  • Supporting blood glucose balance and insulin sensitivity
KSM-66® Ashwagandha (Withania somnifera Root Extract)

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Customer Reviews

Based on 95 reviews
87%
(83)
4%
(4)
6%
(6)
2%
(2)
0%
(0)
A
AB
Quick shipping

No idea if it really works or it’s another fad. Time will tell.

K
Kel
Good products

I am new to these products and so far loving everything I have tried

J
Jonathan Smith
Sun or supplement

Not sure if it was the spring sun or this supplement but after two weeks things have felt on an even keel.

D
Dfletch

Great product

A
Alannah Erskine
Great Product

I love transparent labs for their clean supplements, this ashwagahda has helped me immensely with stress. Shipping was, as always, prompt.

123

How to Use

1
2
1

Step 1 – Take 1 Capsule Daily

Consume one capsule daily with water, with or without food.
2

Step 2 – Optimal Consistency

Use consistently for at least 3-4 weeks to experience maximum stress reduction and cognitive benefits.

Disclaimer: Consult your physician if pregnant, nursing, or taking medications, especially thyroid medications.

Frequently Asked
Questions

What is the difference between Ashwagandha and KSM-66® Ashwagandha?

KSM-66® is a patented organic ashwagandha (Withania somnifera) root extract that is standardized to contain 5% bioactive constituents. Many herbal supplements contain an unspecified/generic ashwagandha root extract that may contain a negligible amount of withanolides, rendering the product less effective. This is why we chose KSM-66® specifically to ensure you get the most effective, potent, and intensively researched ashwagandha extract on the market.

Can you take KSM-66® Ashwagandha every day?

Yes, you can take Ashwagandha daily. As an herbal supplement, Ashwagandha is generally considered safe and can provide continuous benefits for physical and mental stress management, energy levels, and overall well-being.

Does Ashwagandha interfere with thyroid hormone medications?

Ashwagandha may interact with thyroid hormone medications and potentially increase circulating thyroid hormone concentrations in the blood. In a randomized, placebo-controlled study, subclinical hypothyroid patients experienced improvements in thyroid function and levels after taking ashwagandha root extract [RR]. If you're currently taking thyroid medication, consult your healthcare provider before taking ashwagandha extract to avoid any adverse effects.

What Is the difference between Ashwagandha root and leaf extract?

Like a root extract of Ashwagandha, a leaf extract typically contains a dense amount of steroidal lactones (i.e. withanolides), alkaloids, and antioxidants. It's unclear if root and leaf extracts have significantly different effects and they are generally considered interchangeable.

Is there concern for Ashwagandha-induced liver injury?

Although very rare, a few case reports have been published in recent years describing drug-induced hepatocellular injury in subjects who were taking dietary supplements with ashwagandha [RR, RR]. However, many of these case reports involved subjects with pre-existing liver disease/dysfunction, which conflicts with evidence of Ashwagandha supplementation protecting the liver from damage [RR].

Can you drink alcohol while taking KSM-66® Ashwagandha?

Moderate alcohol consumption does not significantly interact with Ashwagandha supplementation, but combining both could potentially amplify sedative effects. It is advisable to avoid heavy alcohol consumption when taking Ashwagandha.

What is the difference between Ashwagandha and KSM-66® Ashwagandha?

KSM-66® is a patented organic ashwagandha (Withania somnifera) root extract that is standardized to contain 5% bioactive constituents. Many herbal supplements contain an unspecified/generic ashwagandha root extract that may contain a negligible amount of withanolides, rendering the product less effective. This is why we chose KSM-66® specifically to ensure you get the most effective, potent, and intensively researched ashwagandha extract on the market.

Can you take KSM-66® Ashwagandha every day?

Yes, you can take Ashwagandha daily. As an herbal supplement, Ashwagandha is generally considered safe and can provide continuous benefits for physical and mental stress management, energy levels, and overall well-being.

Does Ashwagandha interfere with thyroid hormone medications?

Ashwagandha may interact with thyroid hormone medications and potentially increase circulating thyroid hormone concentrations in the blood. In a randomized, placebo-controlled study, subclinical hypothyroid patients experienced improvements in thyroid function and levels after taking ashwagandha root extract [RR]. If you're currently taking thyroid medication, consult your healthcare provider before taking ashwagandha extract to avoid any adverse effects.

What Is the difference between Ashwagandha root and leaf extract?

Like a root extract of Ashwagandha, a leaf extract typically contains a dense amount of steroidal lactones (i.e. withanolides), alkaloids, and antioxidants. It's unclear if root and leaf extracts have significantly different effects and they are generally considered interchangeable.

Is there concern for Ashwagandha-induced liver injury?

Although very rare, a few case reports have been published in recent years describing drug-induced hepatocellular injury in subjects who were taking dietary supplements with ashwagandha [RR, RR]. However, many of these case reports involved subjects with pre-existing liver disease/dysfunction, which conflicts with evidence of Ashwagandha supplementation protecting the liver from damage [RR].

Can you drink alcohol while taking KSM-66® Ashwagandha?

Moderate alcohol consumption does not significantly interact with Ashwagandha supplementation, but combining both could potentially amplify sedative effects. It is advisable to avoid heavy alcohol consumption when taking Ashwagandha.