Synbiotic 3-in-1 for Gut & Immune Health

PreforPro® is a novel phage-based prebiotic containing LH01-Myoviridae, LL5-Siphoviridae, T4D-Myoviridae, and LL12-Myoviridae. Unlike common fiber-based prebiotics, it works by targeting specific unwanted bacteria, releasing nutrients that support beneficial Lactobacillus and Bifidobacterium, to help maintain a balanced gut environment. In randomized, double-blind trials in healthy adults [1,2], PreforPro® used together with Bifidobacterium lactis BL-04® (in our probiotic blend) produced signals for improved GI inflammation and reduced colon-pain scores, plus increases in beneficial bacteria, without disrupting the broader microbial community.

A postbiotic is a non-live (“inanimate”) microbial preparation that still confers a health benefit—unlike probiotics, it doesn’t need to be alive to work. IMMUSE® is a heat-killed form of Lactococcus lactis strain Plasma (LC-Plasma) that activates plasmacytoid dendritic cells (pDCs) coordinating broader innate and adaptive immunity.

IMMUSE® is supported by several peer-reviewed clinical studies for its effects on immune function, recovery, and exercised-induced fatigue. In athletes under high training load, IMMUSE® increased pDC activity and reduced cumulative fatigue days under high training load. [3] Several additional studies have evaluated IMMUSE® in the context of supporting immune function and upper respiratory tract health. [4, 5] 

 This data demonstrates that IMMUSE® helps active individuals keep their immune system ready and functioning optimally for year-round health.

Our 22 Billion CFU Probiotic Blend was purpose-built for healthy, active adults and combines Bifidobacterium lactis BL-04®, Lacticaseibacillus acidophilus NCFM®, B. lactis Bi-07®, and B. animalis subsp. lactis B420™ to support digestive comfort, microbiome balance, and everyday immune health. Probiotics are “good bacteria” that help keep your gut ecosystem in balance, which in turn supports systemic health. We selected strains that complement each other—and that also pair with our PreforPro® phage prebiotic—to help beneficial bacteria thrive and keep your microbiome healthy. Each of these strains and their respective dosages is supported by peer-reviewed clinical studies. BL-04® was linked to a lower risk of upper-respiratory illness in active adults and showed reduced nasal inflammatory response/viral shedding. [6, 7] NCFM® showed alleviation of discomfort in those with pronounced abdominal pain. [8]; the NCFM® + Bi-07® combo can support immune function and exercise readiness in active individuals  [9]; and B420™ can improve body-composition when taken consistently [10]. Notably, PreforPro® + BL-04® together have shown improvements in GI symptoms and increases in beneficial gut bacteria in randomized controlled trials—supporting our prebiotic + probiotic design. [1,2]