Dopamine+

L-Tyrosine is a conditionally essential amino acid and precursor to dopamine and norepinephrine, two neurotransmitters that govern motivation and reward. Research shows that supplementing with L-Tyrosine can significantly enhance cognitive performance, especially under acutely stressful situations (like cramming the night before an exam) [1].

L-Tyrosine has also been shown to improve “cognitive flexibility,” meaning it can help you adapt to changing cognitive demands and block extraneous thoughts [2]. Another study found that L-Tyrosine improves "deep/critical thinking" rather than brainstorming (divergent thinking) [3].

Sabroxy® is a patented herbal extract of Oroxylum indicium that has been shown to possess neuroprotective and cognition-enhancing properties [4]. This specific extract is standardized to contain a minimum 10% oroxylin A, a flavonoid that can inhibit dopamine reuptake, thereby increasing synaptic dopamine levels between nerve cells (neurons) [5]. This mechanism of action supports focus, attention, and cognitive function.

Cognizin® is a patented form of cytidine diphosphate (CDP)-choline, also known as citicoline, that plays a dual role in supporting cognitive function. First, it provides bioavailable choline to support acetylcholine synthesis, a neurotransmitter involved in memory and learning [6]. Second, citicoline supports the production of phosphatidylcholine, a key phospholipid of brain cell membranes, enhancing neuronal communication and dopamine receptor function [7].

Crocins and safranals, the active constituents of saffron, have been shown to increase dopamine levels and improve mood [8]. These compounds can help alleviate symptoms of depression and anxiety, further supporting a focused and positive mental state [9].

Vitamin B6 is a vital cofactor in the synthesis of neurotransmitters, including dopamine. It facilitates the conversion of L-DOPA to dopamine by acting as a coenzyme, thereby enhancing mood and cognitive function [10].

Folate is another essential B vitamin for neurotransmitter production. Specifically, it participates in methylation reactions essential for synthesizing dopamine [11].

Folate's role in maintaining homocysteine levels also supports brain health, further contributing to improved focus and mental clarity [12].