Mushroom Stack

Cordyceps mushrooms have been used for over six centuries in Asian cultures for stimulating appetite, energy, libido, immunity, stamina and enhancing sleep quality. What makes cordyceps unusual is that it is actually a combination of fungus and caterpillar, giving it a unique, elongated shape. 

The primary therapeutic constituents of cordyceps include cordycepin and its derivatives,  polysaccharides, and ergosterol. Research continues to demonstrate that these compounds have a vast range of medicinal actions in humans, including [1]:

• Blood glucose regulation
• Supporting heart health 
• Enhancing kidney function
• Stimulating energy (ATP) production
• Decreasing fatigue from strenuous exercise

Ganoderma lucidum, also known as the reishi mushroom, is a large, robust mushroom that has been used as an immune- and liver-revitalizing agent for centuries in Traditional Chinese Medicine [2]. Reishi mushrooms contain protein and triterpene constituents, specifically ganodermic acids, with potent immunostimulating and hepatoprotective properties [3]. 

Clinical evidence has shown that ganodermic acids inhibit the release of histamine in mast cells (meaning ganodermic acids modulate pro-inflammatory markers in susceptible body tissues) [4]. The distinct proteins in reishi mushrooms also appear to preserve liver function through antioxidant mechanisms [5].

Lion’s Mane (Hericium erinaceus) is a renowned medicinal mushroom due to its strong bioactive properties, notably bolstering and protecting the nervous system and gastrointestinal (GI) function [6]. 

Research has shown that Lion’s Mane strongly reduced ulcer area and inhibited ulcer formation in rats treated with ethanol (to induce ulcers) [6]. Lion’s Mane also helps maintain antioxidant status in the mucosa of the GI tract, an important factor for overall gut health and function. 

Further evidence suggests that Lion’s Mane may have nootropic benefits by promoting the growth and differentiation of neurons in the brain - particularly neurons involved in the cholinergic system [7]. In fact, Lion’s Mane administration increased neurite (dendrites and axons) outgrowth by upwards of 60.6%. This translates to enhanced acetylcholine neurotransmission, an important regulator of cognitive function and focus.